Python Running Python from a USB Drive: A Complete Guide Estimated reading: 3 minutes 777 views Contributors Running Python from a USB Drive: A Complete GuideIf you’re a Python developer who needs to maintain a consistent development environment across multiple machines or work on systems where you cannot install software permanently, running Python from a USB drive could be an ideal solution. This guide will walk you through the steps to set up Python on a USB drive, making your programming environment portable and accessible anywhere.Choosing the Right Python DistributionBefore you start, you’ll need to decide on a Python distribution that supports portability. Some popular choices include:WinPython: This is a free open-source portable distribution of Python for Windows. It is designed to be as portable and flexible as possible, making it ideal for USB drives. Portable Python (No longer actively maintained): Although it’s no longer maintained, older versions of Portable Python can still be used and come pre-packaged with additional Python tools.For this guide, we’ll use WinPython due to its active maintenance and compatibility with the latest Python versions.Step 1: Download WinPythonVisit the WinPython GitHub page and download the latest version of WinPython that matches your system architecture (32-bit or 64-bit). Choose a version that suits your needs. If you’re unsure, the standard version usually suffices for most general programming tasks.Step 2: Install WinPython on Your USB DriveOnce the download is complete, extract the ZIP file directly to the root directory of your USB drive. Open the extracted folder and run the WinPython Control Panel. This step is optional but recommended for managing packages and environments directly from your USB drive.Step 3: Configure WinPython (Optional)In the WinPython Control Panel, you can manage Python packages using the embedded pip interface. You can also adjust environment variables and paths if necessary, though WinPython is designed to handle most of this automatically.Step 4: Create a Portable Python WorkspaceOn your USB drive, create a new folder where you will store all your Python scripts and projects. This helps in keeping your work organized and separate from the Python installation. You can launch Python directly from the USB by running python.exe from the scripts folder inside the WinPython directory on your USB drive.Step 5: Running Your First ScriptOpen a text editor like Notepad++ (which can also be run portably), and write a simple Python script. print("Hello, Python from USB!") Save this script in the workspace folder you created on your USB drive. Open a command prompt from the scripts folder by running WinPython Command Prompt.exe. Navigate to your workspace folder: cd /path/to/your/workspace Run your script: python yourscript.pyConclusionRunning Python from a USB drive provides flexibility and convenience, especially for those who work on multiple computers or restricted systems. With WinPython, you can easily carry your development environment in your pocket, ensuring that you have access to your Python projects and tools at all times. Just remember that running applications from a USB drive can be slower than running them from an internal hard drive, so patience is sometimes required. Happy coding on the go!